In Pathogenic, you are the disease.

Experience a visceral 2D roguelike twin-stick shooter where you play as a lone parasite fighting a desperate war against the immune system. Your goal is simple: infect and completely conquer your human host.

To survive, you must adapt. Hunt down enemy cells, rip out their organelles, and graft them onto your own body. Evolve from a simple cell into a complex engine of destruction, creating powerful, game-breaking builds to become the ultimate pathogen.

CREATE YOUR OWN PATHOGEN

Loot, graft, and assemble your parasite from dozens of unique organelles. Combine lashes for movement, mitochondria for power, secretors for ranged attacks, and spikes for melee combat. Discover powerful synergies to build an unstoppable disease.

FIGHT THE IMMUNE SYSTEM

Battle a diverse roster of enemies, from basic immune cells like macrophages and T-cells to rival parasites such as tapeworms or protozoa. Formidable bosses are lurking deep within the host's organs.

EXPLORE A MICROSCOPIC WORLD

Navigate the human body, a procedurally generated world of organic wonder. Travel through distinct biomes like the branching pathways of the lungs, the pulsating chambers of the heart, and the complex neural network of the brain.

FEEL THE ORGANIC ACTION

Our detailed, colorful world is powered by a soft-body physics simulation, giving every cell, enemy, and projectile a uniquely satisfying organic feel. The combination of hand-crafted design and procedural generation ensures that no two runs are ever the same, offering endless, challenging gameplay that always stays fresh.